EXAMINE THIS REPORT ON LDN-27219 POTENTIAL THERAPEUTIC APPLICATIONS

A single specifically fascinating compound is LDN-27219. Though most tTG inhibitors are built to bind on the protein crosslinking active web-site, LDN-27219 as a substitute binds for the nucleotide binding pocket of your enzyme when it truly is in its shut-state conformation, and stabilizes that conformation to circumvent crosslinking activity.78 S